Teva’s Naloxone HCl Nasal Spray is a medicine used for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.

Teva’s Naloxone HCl Nasal Spray is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after giving the first dose of Teva’s Naloxone HCl Nasal Spray, even if the person wakes up.

Teva’s Naloxone HCl Nasal Spray is safe and effective in children for known or suspected opioid overdose.

Yes, Teva’s Naloxone HCl Nasal Spray has the same active ingredient as Narcan^® Nasal Spray. It works in the body the same way as Narcan^® Nasal Spray in the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.

Opioids are a class of drugs used to reduce pain. Learn more about opioids here.

Use Teva’s Naloxone HCl Nasal Spray right away when an opioid emergency is known or suspected. Signs of an opioid emergency may include:

• unusual sleepiness and you are not able to awaken the person with a loud voice or by rubbing firmly on the middle of their chest (sternum)
• breathing problems including slow or shallow breathing in someone difficult to awaken or who looks like they are not breathing
• the black circle in the center of the colored part of the eye (pupil) is very small, sometimes called “pinpoint pupils,” in someone difficult to awaken

Teva’s Naloxone HCl Nasal Spray is used to temporarily reverse the effects of opioid medicines. The medicine in Teva’s Naloxone HCl Nasal Spray has no effect in people who are not taking opioid medicines. Always carry Teva’s Naloxone HCl Nasal Spray with you in case of an opioid emergency.

1. Use Teva’s Naloxone HCl Nasal Spray right away if you or your caregiver think signs or symptoms of an opioid emergency are present, even if you are not sure, because an opioid emergency can cause severe injury or death. Signs and symptoms of an opioid emergency may include:
   • unusual sleepiness and you are not able to awaken the person with a loud voice or by rubbing firmly on the middle of their chest (sternum)
   • breathing problems including slow or shallow breathing in someone difficult to awaken or who looks like they are not breathing
   • the black circle in the center of the colored part of the eye (pupil) is very small, sometimes called “pinpoint pupils,” in someone difficult to awaken
2. Family members, caregivers, or other people who may have to use Teva’s Naloxone HCl Nasal Spray in an opioid emergency should know where Teva’s Naloxone HCl Nasal Spray is stored and how to give naloxone hydrochloride before an opioid emergency happens.
3. Get emergency medical help right away after giving the first dose of Teva’s Naloxone HCl Nasal Spray. Rescue breathing or CPR (cardiopulmonary resuscitation) may be given while waiting for emergency medical help.
4. The signs and symptoms of an opioid emergency can return after Teva’s Naloxone HCl Nasal Spray is given. If this happens, give another dose after 2 to 3 minutes using a new Naloxone HCl Nasal Spray device and watch the person closely until emergency help is received.

For information on how to use Teva’s Naloxone HCl Nasal Spray, visit the How to Use section of this website, or read the Instructions for Use in the full Prescribing Information.

Teva’s Naloxone HCl Nasal Spray is not a substitute for emergency medical care. You should still get emergency medical help right away. After administering Teva’s Naloxone HCl Nasal Spray, move the person to their side (recovery position) and watch the person carefully. If the person does not respond by waking up, to voice or touch, or breathing normally another dose may be given. Teva’s Naloxone HCl Nasal Spray may be dosed every 2 to 3 minutes, if available.

Teva’s Naloxone HCl Nasal Spray may cause serious side effects, including:

• Sudden opioid withdrawal symptoms. In someone who has been using opioids regularly, opioid withdrawal symptoms can happen suddenly after receiving Teva’s Naloxone HCl Nasal Spray and may include: body aches, diarrhea, increased heart rate, fever, runny nose, sneezing, goose bumps, sweating, yawning, nausea or vomiting, nervousness, restlessness or irritability, shivering or trembling, stomach cramping, weakness, or increased blood pressure.

In infants under 4 weeks old who have been receiving opioids regularly, sudden opioid withdrawal may be life-threatening if not treated the right way. Signs and symptoms include: seizures, crying more than usual, and increased reflexes.

These are not all of the possible side effects of Teva’s Naloxone HCl Nasal Spray. Call your doctor for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

No. Each Naloxone HCl Nasal Spray device contains only 1 dose of medicine and cannot be reused.

Store below 77°F (25°C). Excursions permitted up to 104°F (40°C). Do not freeze or expose to excessive heat above 104°F (40°C).

Keep Teva’s Naloxone HCl Nasal Spray in its box until ready to use. Protect from light. Replace Teva’s Naloxone HCl Nasal Spray before the expiration date on the box. Keep Teva’s Naloxone HCl Nasal Spray and all medicines out of the reach of children.